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Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides.

Trayssac M, Clarke CJ, Stith JL, Snider JM, Newen N, Gault CR, Hannun YA, Obeid LM
Cell Death Dis. 2021 Jan 4;12(1):27. doi: 10.1038/s41419-020-03281-4. (Link opens in a new window) PubMed (Link opens in a new window) Article

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