NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.
Zhang SM, Rehling D, Jemth AS, Throup A, Landazuri N, Almlof I, Gottmann M, Valerie NCK, Borhade SR, Wakchaure P, Page BDG, Desroses M, Homan EJ, Scobie M, Rudd SG, Berglund UW, Soderberg-Naucler C, Stenmark P, Helleday T
Cell Chem Biol. 2021 Jun 22. pii: S2451-9456(21)00268-3. doi: 10.1016/j.chembiol.2021.06.001.
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