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Recording of cellular physiological histories along optically readable self-assembling protein chains.
Linghu C, An B, Shpokayte M, Celiker OT, Shmoel N, Zhang R, Zhang C, Park D, Park WM, Ramirez S, Boyden ES
Nat Biotechnol. 2023 Jan 2. doi: 10.1038/s41587-022-01586-7.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
178056pAAV-UBC-XRI-HAExpression Recording Islands (XRIs) for recording cellular physiological histories along intracellular protein self-assembly. Contains XRI subunit with HA tag, under UBC promoter.
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178057pAAV-UBC-FLEX-XRI-FLAGExpression Recording Islands (XRIs) for recording cellular physiological histories along intracellular protein self-assembly. Contains XRI subunit with FLAG tag, under UBC promoter with a FLEX switch.
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178058pAAV-cFos-XRI-V5Expression Recording Islands (XRIs) for recording cellular physiological histories along intracellular protein self-assembly. Contains XRI subunit with V5 tag, under c-fos promoter.
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178059pAAV-Syn-ERT2-iCre-ERT2Conditionally active form of Cre recombinase (activated in response to tamoxifen) under Syn promoter.
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178060pAAV-UBC-ERT2-iCre-ERT2Conditionally active form of Cre recombinase (activated in response to tamoxifen) under UBC promoter.
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Antibodies from Article