eccDNAs are apoptotic products with high innate immunostimulatory activity.

Wang Y, Wang M, Djekidel MN, Chen H, Liu D, Alt FW, Zhang Y
Nature. 2021 Nov;599(7884):308-314. doi: 10.1038/s41586-021-04009-w. Epub 2021 Oct 20. PubMed Article

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