The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Iennaco R, Formenti G, Trovesi C, Rossi RL, Zuccato C, Lischetti T, Bocchi VD, Scolz A, Martinez-Labarga C, Rickards O, Pacifico M, Crottini A, Moller AP, Chen RZ, Vogt TF, Pavesi G, Horner DS, Saino N, Cattaneo E
Cell Death Differ. 2022 Feb;29(2):293-305. doi: 10.1038/s41418-021-00914-9. Epub 2022 Jan 1.
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