Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice.

Duan Y, Ye T, Qu Z, Chen Y, Miranda A, Zhou X, Lok KC, Chen Y, Fu AKY, Gradinaru V, Ip NY
Nat Biomed Eng. 2022 Feb;6(2):168-180. doi: 10.1038/s41551-021-00759-0. Epub 2021 Jul 26. PubMed Article

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