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SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling.

Fedele C, Li S, Teng KW, Foster CJR, Peng D, Ran H, Mita P, Geer MJ, Hattori T, Koide A, Wang Y, Tang KH, Leinwand J, Wang W, Diskin B, Deng J, Chen T, Dolgalev I, Ozerdem U, Miller G, Koide S, Wong KK, Neel BG
J Exp Med. 2021 Jan 4;218(1). pii: 211451. doi: 10.1084/jem.20201414. (Link opens in a new window) PubMed (Link opens in a new window) Article

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