The Pol II preinitiation complex (PIC) influences Mediator binding but not promoter-enhancer looping.

Sun F, Sun T, Kronenberg M, Tan X, Huang C, Carey MF
Genes Dev. 2021 Aug 1;35(15-16):1175-1189. doi: 10.1101/gad.348471.121. Epub 2021 Jul 22. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.