CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma.

Yao J, Wang J, Xu Y, Guo Q, Sun Y, Liu J, Li S, Guo Y, Wei L
Autophagy. 2022 Aug;18(8):1879-1897. doi: 10.1080/15548627.2021.2007027. Epub 2021 Dec 10. PubMed Article

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