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Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes.

LaRock DL, Johnson AF, Wilde S, Sands JS, Monteiro MP, LaRock CN
Nature. 2022 May;605(7910):527-531. doi: 10.1038/s41586-022-04717-x. Epub 2022 May 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
218935pCMV-Flag-hGSDMAExpression of N-terminal FLAG tagged human gasdermin A
218936pCMV-Flag-hGSDMBExpression of N-terminal FLAG tagged human gasdermin B
218937pCMV-Flag-hGSDMCExpression of N-terminal FLAG tagged human gasdermin C
218938pCMV-Flag-hGSDMDExpression of N-terminal FLAG tagged human gasdermin D
218939pCMV-Flag-hGSDMEExpression of N-terminal FLAG tagged human gasdermin E
218940pCMV-Flag-mGSDMA1Expression of N-terminal FLAG tagged mouse gasdermin A1
218941pCMV-Flag-mGSDMA2Expression of N-terminal FLAG tagged mouse gasdermin A2
218942pCMV-Flag-mGSDMA3Expression of N-terminal FLAG tagged mouse gasdermin A3

Antibodies from Article