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Unprotected peptide macrocyclization and stapling via a fluorine-thiol displacement reaction.

Islam MS, Junod SL, Zhang S, Buuh ZY, Guan Y, Zhao M, Kaneria KH, Kafley P, Cohen C, Maloney R, Lyu Z, Voelz VA, Yang W, Wang RE
Nat Commun. 2022 Jan 17;13(1):350. doi: 10.1038/s41467-022-27995-5. (Link opens in a new window) PubMed (Link opens in a new window) Article

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