HER2 mediates clinical resistance to the KRAS(G12C) inhibitor sotorasib, which is overcome by co-targeting SHP2.

Ho CSL, Tuns AI, Schildhaus HU, Wiesweg M, Gruner BM, Hegedus B, Schuler M, Schramm A, Oeck S
Eur J Cancer. 2021 Dec;159:16-23. doi: 10.1016/j.ejca.2021.10.003. Epub 2021 Oct 26. PubMed Article

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