Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction.

Liu Z, Yang N, Dong J, Tian W, Chang L, Ma J, Guo J, Tan J, Dong A, He K, Zhou J, Cinar R, Wu J, Salinas AG, Sun L, Kumar M, Sullivan BT, Oldham BB, Pitz V, Makarious MB, Ding J, Kung J, Xie C, Hawes SL, Wang L, Wang T, Chan P, Zhang Z, Le W, Chen S, Lovinger DM, Blauwendraat C, Singleton AB, Cui G, Li Y, Cai H, Tang B
Nat Commun. 2022 Jun 17;13(1):3490. doi: 10.1038/s41467-022-31168-9. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
239421	pAAV-CMV-DIO-SaCas9-U6-sgDagla	Knockdown expression of Dagla
240023	pAAV-CMV-DIO-SaCas9-U6-sgDaglb	Knockdown expression of Daglb