Losartan metabolite EXP3179 is a unique blood pressure-lowering AT1R antagonist with direct, rapid endothelium-dependent vasoactive properties.
Sauge E, Pechkovsky D, Atmuri NDP, Tehrani AY, White Z, Dong Y, Cait J, Hughes M, Tam A, Donen G, Yuen C, Walker MJA, McNagny KM, Sin DD, Ciufolini MA, Bernatchez P
Vascul Pharmacol. 2022 Dec;147:107112. doi: 10.1016/j.vph.2022.107112. Epub 2022 Sep 27.
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