DHODH inhibition impedes glioma stem cell proliferation, induces DNA damage, and prolongs survival in orthotopic glioblastoma xenografts.
Spina R, Mills I, Ahmad F, Chen C, Ames HM, Winkles JA, Woodworth GF, Bar EE
Oncogene. 2022 Dec;41(50):5361-5372. doi: 10.1038/s41388-022-02517-1. Epub 2022 Nov 7.
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