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The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.

Schembs L, Willems A, Hasenpusch-Theil K, Cooper JD, Whiting K, Burr K, Bostrand SMK, Selvaraj BT, Chandran S, Theil T
Cell Rep. 2022 May 17;39(7):110811. doi: 10.1016/j.celrep.2022.110811. (Link opens in a new window) PubMed (Link opens in a new window) Article

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