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Discovery of Dual TAF1-ATR Inhibitors and Ligand-Induced Structural Changes of the TAF1 Tandem Bromodomain.

Karim RM, Yang L, Chen L, Bikowitz MJ, Lu J, Grassie D, Shultz ZP, Lopchuk JM, Chen J, Schonbrunn E
J Med Chem. 2022 Mar 10;65(5):4182-4200. doi: 10.1021/acs.jmedchem.1c01999. Epub 2022 Feb 22. (Link opens in a new window) PubMed (Link opens in a new window) Article

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