Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice.

Gul S, Akyel YK, Gul ZM, Isin S, Ozcan O, Korkmaz T, Selvi S, Danis I, Ipek OS, Aygenli F, Taskin AC, Akarlar BA, Ozlu N, Ozturk N, Ozturk N, Unal DO, Guzel M, Turkay M, Okyar A, Kavakli IH
Nat Commun. 2022 Nov 8;13(1):6742. doi: 10.1038/s41467-022-34582-1. PubMed Article

Plasmids from Article

No plasmids are currently publicly available from Addgene for this article.