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Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor.

Bhattacharjee D, Bakar J, Chitnis SP, Sausville EL, Ashtekar KD, Mendelson BE, Long K, Smith JC, Heppner DE, Sheltzer JM
Cell Chem Biol. 2023 Oct 19;30(10):1211-1222.e5. doi: 10.1016/j.chembiol.2023.09.013. Epub 2023 Oct 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
200973Lenti-MAPK14a mammalian expression vector to express MAPK14

Antibodies from Article