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Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS.
Jourdain AA, Begg BE, Mick E, Shah H, Calvo SE, Skinner OS, Sharma R, Blue SM, Yeo GW, Burge CB, Mootha VK
Mol Cell. 2021 May 6;81(9):1905-1919.e12. doi: 10.1016/j.molcel.2021.02.033. Epub 2021 Apr 13.
PubMed Article

Plasmids from Article

ID Plasmid Purpose
201588LENTICRISPR-ACIN1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201589LENTICRISPR-ACIN1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201592LENTICRISPR-ENO1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201593LENTICRISPR-ENO1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201596LENTICRISPR-HK2_sgRNA1CRISPR/Cas9-mediated gene knock-out
201597LENTICRISPR-HK2_sgRNA2CRISPR/Cas9-mediated gene knock-out
201598LENTICRISPR-HNRNPD_sgRNA1CRISPR/Cas9-mediated gene knock-out
201599LENTICRISPR-HNRNPD_sgRNA2CRISPR/Cas9-mediated gene knock-out
201600LENTICRISPR-LUC7L_sgRNA1CRISPR/Cas9-mediated gene knock-out
201601LENTICRISPR-LUC7L_sgRNA2CRISPR/Cas9-mediated gene knock-out
201602LENTICRISPR-LUC7L2_sgRNA1CRISPR/Cas9-mediated gene knock-out
201603LENTICRISPR-LUC7L2_sgRNA2CRISPR/Cas9-mediated gene knock-out
201604LENTICRISPR-LUC7L3_sgRNA1CRISPR/Cas9-mediated gene knock-out
201605LENTICRISPR-LUC7L3_sgRNA2CRISPR/Cas9-mediated gene knock-out
201606LENTICRISPR-NDUFB5_sgRNA1CRISPR/Cas9-mediated gene knock-out
201607LENTICRISPR-NDUFB5_sgRNA2CRISPR/Cas9-mediated gene knock-out
201608LENTICRISPR-PABPC1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201609LENTICRISPR-PABPC1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201610LENTICRISPR-PFKM_sgRNA1CRISPR/Cas9-mediated gene knock-out
201611LENTICRISPR-PFKM_sgRNA2CRISPR/Cas9-mediated gene knock-out
201614LENTICRISPR-PGAM1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201615LENTICRISPR-PGAM1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201620LENTICRISPR-SNRNP70_sgRNA1CRISPR/Cas9-mediated gene knock-out
201621LENTICRISPR-SNRNP70_sgRNA2CRISPR/Cas9-mediated gene knock-out
201622LENTICRISPR-SNRPA_sgRNA1CRISPR/Cas9-mediated gene knock-out
201623LENTICRISPR-SNRPA_sgRNA2CRISPR/Cas9-mediated gene knock-out
201626LENTICRISPR-TPI1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201627LENTICRISPR-TPI1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201636pLV-EF1a-IRES-Puro GFP-3xFLAG Over-expression of 3xFLAG-tagged GFP
201638pLV-EF1a-IRES-Puro PFKM Over-expression of untagged human PFKM
201640pWPI-LUC7L-3xFLAGOver-expression of 3xFLAG-tagged human LUC7L
201641pWPI-LUC7L2-3xFLAGOver-expression of 3xFLAG-tagged human LUC7L2
201643pWPI-SLC7A11-HAOver-expression of HA-tagged human SLC7A11

Antibodies from Article