The N-terminal domain of human mitochondrial helicase Twinkle has DNA-binding activity crucial for supporting processive DNA synthesis by polymerase gamma.
Johnson LC, Singh A, Patel SS
J Biol Chem. 2023 Jan;299(1):102797. doi: 10.1016/j.jbc.2022.102797. Epub 2022 Dec 14.
(Link opens in a new window)
PubMed
(Link opens in a new window)
Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 205054 | SUMO-Twinkle 43-372 | TWNK protein expression |
| 205055 | SUMO-Twinkle 360-684 | TWNK protein expression |
| 205056 | SUMO-Twinkle 43-684 | TWNK protein expression |
| 205057 | mt SSB | SSB1 protein expression |