TLNRD1 is a CCM complex component and regulates endothelial barrier integrity
Neil J. Ball, Sujan Ghimire, Gautier Follain, Ada O. Pajari, Monika Vaitkevičiūtė, Alana R. Cowell, Bence Berki, Johanna Ivaska, ProfileIlkka Paatero, Benjamin T. Goult, Guillaume Jacquemet
BioRxiv Article
Neil J. Ball, Sujan Ghimire, Gautier Follain, Ada O. Pajari, Monika Vaitkevičiūtė, Alana R. Cowell, Bence Berki, Johanna Ivaska, ProfileIlkka Paatero, Benjamin T. Goult, Guillaume Jacquemet
BioRxiv Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 208861 | TLNRD1_5H_eGFP | Express eGFP-TLNRD1 5 helix bundle (TLNRD1 lacking amino acids 142-273) in mammalian cells. |
| 208876 | CCM2_wt_eGFP | Express eGFP-CCM2 in mammalian cells. |
| 208877 | CCM2_d410-444_eGFP | Express eGFP-CCM2 lacking amino acids 410-444 in mammalian cells. |
| 208878 | CCM2_I428S_eGFP | Express eGFP-CCM2 with the I428S mutation in mammalian cells. |
| 208879 | CCM2_I432D_eGFP | Express eGFP-CCM2 with the I432D mutation in mammalian cells. |
| 208880 | CCM2_W421AD422A_eGFP | Express eGFP-CCM2 with the W421A and D422A mutations in mammalian cells. |
| 208881 | TLNRD1_35-345_eGFP | Express eGFP-TLNRD1 lacking N and Cterm domains (TLNRD1 amino acids 35-345) in mammalian cells. |
| 208883 | TLNRD1_2T_eGFP | Express eGFP-TLNRD1 with the L191T and A225T mutations in mammalian cells. |
| 208884 | TLNRD1_2E_eGFP | Express eGFP-TLNRD1 with the K192E and R233E mutations in mammalian cells. |
| 208886 | mito-CCM2-mScarlet-I | Express mScarlet-I-CCM2 targeted to the mitochondria in mammalian cells. |
| 208887 | mito-PDCD10-mScarlet-I | Express mScarlet-I-PDCD10 targeted to the mitochondria in mammalian cells. |