PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth.
Kozlov G, Funato Y, Chen YS, Zhang Z, Illes K, Miki H, Gehring K
J Biol Chem. 2020 Aug 14;295(33):11682-11692. doi: 10.1074/jbc.RA120.014464. Epub 2020 Jun 22.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 209792 | hPRL1_1-169 | Bacterial expression of human PRL-1 without farnesylation motif |
| 209793 | hPRL1_1-169_C104D | Bacterial expression of human PRL-1 C104D mutant without farnesylation motif |
| 209794 | hPRL2_1-163 | Bacterial expression of human PRL-2 without farnesylation motif |
| 209797 | hPRL3_1-169_C104D | Bacterial expression of human PRL-3 C104D mutant without farnesylation motif |