Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition.
    
      Nam M, Xia W, Mir AH, Jerrett A, Spinelli JB, Huang TT, Possemato R
    
    
      Nat Metab. 2024 Dec;6(12):2338-2353. doi: 10.1038/s42255-024-01166-w. Epub 2024 Nov 26.
    
    
      
        
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Plasmids from Article
| ID | Plasmid | Purpose | 
|---|---|---|
| 211519 | pLentiCRISPR-v2 sgCASP8 | Deletes CASP8 | 
| 211520 | pLentiCRISPR-v2 sgBAK1 | Deletes BAK1 | 
| 211521 | pLentiCRISPR-v2 sgUGP2 | Deletes UGP2 | 
| 211522 | pLentiCRISPR-v2 sgUCK2 | Deletes UCK2 | 
| 211523 | pLentiCRISPR-v2 sgUCKL1 | Deletes UCKL1 | 
| 211524 | pLentiCRISPR-v2 hygro sgUCK1 | Deletes UCK1 | 
| 211525 | pSECB sgCASP9 | Deletes CASP9 | 
| 211526 | BPK1520 sgRPS3 | Facilitate knock-in of RPS3-Keima fusion protein | 
| 211527 | BPK1520 sgFADD | Deletes FADD | 
| 211528 | LV-sgRNA-mCherry-Puro sgPIDD | Deletes PIDD | 
| 211529 | pLJM1 flag-cFLIP | Expresses flag-tagged cFLIP (CFLAR) | 
| 211530 | pMXS-IRES-Blast coUCK2 D62A | Expresses codon optimized catalytic mutant UCK2 | 
| 211531 | pMXS-IRES-Blast coUGP2 | Expresses codon optimized UGP2 | 
| 211533 | pCW57.1 blast tBID-flag | Expresses truncated BID upon doxycycline addition to trigger apoptosis | 
| 211534 | pLentiCRISPR-v2 sgATG7 | Deletes ATG7 |