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Randomizing the human genome by engineering recombination between repeat elements.

Koeppel J, Ferreira R, Vanderstichele T, Riedmayr LM, Peets EM, Girling G, Weller J, Murat P, Liberante FG, Ellis T, Church GM, Parts L
Science. 2025 Jan 31;387(6733):eado3979. doi: 10.1126/science.ado3979. Epub 2025 Jan 31. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
216866pLenti-ePEG-LINE1-loxPsymLentiviral guide RNA vector to insert the loxPsym sequence into LINE1 elements

Antibodies from Article