Optogenetic engineering of STING signaling allows remote immunomodulation to enhance cancer immunotherapy.
Dou Y, Chen R, Liu S, Lee YT, Jing J, Liu X, Ke Y, Wang R, Zhou Y, Huang Y
Nat Commun. 2023 Sep 6;14(1):5461. doi: 10.1038/s41467-023-41164-2.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
238371 | pMSCV-GFP-IRES-CRY2clust-pLxIS | Retroviral expression construct encoding CRY2clust fused to two copies of the C-terminal tail of human STING |