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Optogenetic engineering of STING signaling allows remote immunomodulation to enhance cancer immunotherapy.

Dou Y, Chen R, Liu S, Lee YT, Jing J, Liu X, Ke Y, Wang R, Zhou Y, Huang Y
Nat Commun. 2023 Sep 6;14(1):5461. doi: 10.1038/s41467-023-41164-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
238371pMSCV-GFP-IRES-CRY2clust-pLxISRetroviral expression construct encoding CRY2clust fused to two copies of the C-terminal tail of human STING

Antibodies from Article