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Rab8 and TNPO1 are ciliary transport adaptors for GTPase Arl13b by interacting with its RVEP motif containing ciliary targeting sequence.

Mahajan D, Madugula V, Lu L
J Biol Chem. 2023 May;299(5):104604. doi: 10.1016/j.jbc.2023.104604. Epub 2023 Mar 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
221161Arl13b-RVEP-4A-GFPExpresses mammalian Arl13b with RVEP4A mutation and GFP-tagged
221175PAL-GFPExpresses the palmitolylation region of Arl13b and GFP-tagged
221176PAL-AA248-428-GFPExpresses the palmitolylation region and amino acids 248-428 of mamalian Arl13b and GFP-tagged
221591PAL-AA246–324-GFPExpresses the palmitolylation region of mamalian Arl13b (amino acids 246-325) and GFP-tagged
221592PAL-13bCTS-GFPExpresses the palmitoylation sequence, the ciliary targeting sequence of mammalian Arl13b (amino acids 347-363) and GFP-tagged
221593PAL-AA347-363-RVEP-4A-GFPExpresses the palmitoylation sequence, the ciliary targeting sequence with RVEP4A mutation of mammalian Arl13b (amino acids 347-363) and GFP-tagged
221596CD8a-AA347-363-GFPExpresses CD8a with ciliary targeting sequence (CTS) from amino acids 347-363 of Arl13b fused to the cytosolic tail and GFP-tagged
221597CD8a-AA347-363- RVEP-4A-GFPExpresses CD8a with of Arl13b ciliary targeting sequence (CTS) from amino acids 347-363 with RVEP4A mutation fused to the cytosolic tail and GFP-tagged
221598CD8a-AA347-363-KRN-3A-GFPExpresses CD8a with of Arl13b ciliary targeting sequence (CTS) from amino acids 347-363 with KRN-3A mutation fused to the cytosolic tail and GFP-tagged
221599CD8a-AA354-363-GFPExpresses CD8a fused with a segment of the Arl13b protein (amino acids 354-363) and GFP-tagged
247082AA1-245-GFPExpresses mammalian Arl13b with amino acids 1-245 and GFP-tagged
247240His-AA1-245-GFPA bacterial expression plasmid encoding Arl13b (aa1-245) with N-terminal His and GFP-tagged
247241His-AA195-428-GFPA bacterial expression plasmid encoding Arl13b (aa195-428) with N-terminal His and GFP-tagged
247242His-GFPA bacterial expression plasmid encoding GFP with N-terminal His
247243His-13bCTS-GFPA bacterial expression plasmid encoding ciliary targeting sequence of mammalian Arl13b (amino acids 347-363) with N-terminal His and GFP-tagged
247244His-MBP-GFPA bacterial expression plasmid encoding maltose binding protein with N-terminal His and GFP-tagged
247762CD8a-AA354-361-GFPExpresses CD8a fused with a segment of the Arl13b protein (amino acids 354-361) and GFP-tagged
247767CD8a-AA358-361-GFPExpresses CD8a fused with a segment of the Arl13b protein (amino acids 358-361) and GFP-tagged

Antibodies from Article