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Continuous evolution of user-defined genes at 1 million times the genomic mutation rate.

Rix G, Williams RL, Hu VJ, Spinner A, Pisera AO, Marks DS, Liu CC
Science. 2024 Nov 8;386(6722):eadm9073. doi: 10.1126/science.adm9073. Epub 2024 Nov 8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
222013pGR721 - SLD3p-TP-DNAP1.Badboy2Expresses the Badboy2 TP-DNAP1 variant under control of a weak promoter for reducing p1 copy number

Antibodies from Article