A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation.
Ali RH, Orellana EA, Lee SH, Chae YC, Chen Y, Clauwaert J, Kennedy AL, Gutierrez AE, Papke DJ, Valenzuela M, Silverman B, Falzetta A, Ficarro SB, Marto JA, Fletcher CDM, Perez-Atayde A, Alcindor T, Shimamura A, Prensner JR, Gregory RI, Gutierrez A
Mol Cell. 2025 Mar 6;85(5):948-961.e11. doi: 10.1016/j.molcel.2025.01.003. Epub 2025 Jan 31.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 223023 | rag2:OS9_CE_pISceI | Express OS9 gene in mesenchymal lineage of Zebrafish. |
| 223024 | rag2:AGAP2_CE_pISceI | Express AGAP2 gene in mesenchymal lineage of Zebrafish. |
| 223025 | rag2:TSPAN31_CE_pISceI | Express TSPAN31 gene in mesenchymal lineage of Zebrafish. |
| 223026 | rag2:CDK4_CE_pISceI | Express CDK4 gene in mesenchymal lineage of Zebrafish. |
| 223027 | rag2:MARCH9_CE_pISceI | Express MARCH--9 gene in mesenchymal lineage of Zebrafish. |
| 223028 | rag2:CYP27B1_CE_pISceI | Express CYP27B1 gene in mesenchymal lineage of Zebrafish. |
| 223029 | rag2:METTL1_CE_pISceI | Express METTL1 gene in mesenchymal lineage of Zebrafish. |
| 223030 | rag2:METTL121B_CE_pISceI | Express METTL121B gene in mesenchymal lineage of Zebrafish. |
| 223031 | rag2:TSFM_CE_pISceI | Express TSFM gene in mesenchymal lineage of Zebrafish. |
| 223032 | rag2:AVIL_CE_pISceI | Express AVIL gene in mesenchymal lineage of Zebrafish. |
| 223033 | rag2:CTDSP2_CE_pISceI | Express CTDSP2 gene in mesenchymal lineage of Zebrafish. |
| 223034 | rag2:HMGA2_CE_pISceI | Express HMGA2 gene in mesenchymal lineage of Zebrafish. |
| 223035 | rag2:MDM2_CE_pISceI | Express MDM2 gene in mesenchymal lineage of Zebrafish. |
| 223036 | rag2:CPM_CE_pISceI | Express CPM gene in mesenchymal lineage of Zebrafish. |
| 223037 | rag2:CPSF6_CE_pISceI | Express CPSF6 gene in mesenchymal lineage of Zebrafish. |
| 223038 | rag2:LYZ_CE_pISceI | Express LYZ gene in mesenchymal lineage of Zebrafish. |
| 223039 | rag2:YEATS4_CE_pISceI | Express YEATS4 gene in mesenchymal lineage of Zebrafish. |
| 223040 | rag2:FRS2_CE_pISceI | Express FRS2 gene in mesenchymal lineage of Zebrafish. |
| 223041 | rag2:CCT2_CE_pISceI | Express CCT2 gene in mesenchymal lineage of Zebrafish. |
| 223042 | rag2:LRRC10_CE_pISceI | Express LRRC10 gene in mesenchymal lineage of Zebrafish. |
| 223043 | rag2:BEST3_CE_pISceI | Express BEST3 gene in mesenchymal lineage of Zebrafish. |
| 223044 | rag2:RAB3IP_CE_pISceI | Express RAB3IP gene in mesenchymal lineage of Zebrafish. |
| 223045 | rag2:MYRFL_CE_pISceI | Express MYRFL gene in mesenchymal lineage of Zebrafish. |
| 223046 | rag2:CNOT_CE_pISceI | Express CNOT2 gene in mesenchymal lineage of Zebrafish. |
| 223047 | rag2:mcherry_CE_pISceI | Express m-Cherry gene in mesenchymal lineage of Zebrafish. |
| 223048 | rag2:METTL1-S27A_CE_pISceI | Express METTL1-S27A gene in mesenchymal lineage of Zebrafish. |
| 223049 | rag2:METTL1-S27D_CE_pISceI | Express METTL1-S27D gene in mesenchymal lineage of Zebrafish. |
| 223050 | rag2:METTL1-CM_CE_pISceI | Express METTL1-CM gene in mesenchymal lineage of Zebrafish. |
| 223051 | rag2:WDR4_CE_pISceI | Express WDR4 gene in mesenchymal lineage of Zebrafish. |
| 223052 | pdest EGFP Neo | EGFP gene expression in mammalian cells |
| 223053 | pdest myr-AKT2 puro | myr-AKT2 gene expression in mammalian cells |
| 223054 | pdest dTomato Puro | dTomato gene expression in mammalian cells |
| 223055 | pdest N-FLAG METTL1-WT puro | METTL1-WT gene expression in mammalian cells |
| 223056 | pdest N-FLAG EGFP puro | EGFP gene expression in mammalian cells |
| 223058 | pdest METTL1-WT Neo | METTL1 gene expression in mammalian cells |
| 223059 | pdest METTL1-S27A Neo | METTL1-S27A gene expression in mammalian cells |
| 223060 | pdest METTL1-S27D Neo | METTL1-S27D gene expression in mammalian cells |
| 223061 | pdest METTL1-CM Neo | METTL1-CM gene expression in mammalian cells |
| 223062 | pdest WDR4 Puro | WDR4 gene expression in mammalian cells |
| 223063 | pdest myr-AKT2 Neo | myr-AKT2 gene expression in mammalian cells |
| 231495 | rag2:myr-Akt2_pISceI | Expresses myristolated Akt2 in zebrafish lymphoid and mesenchymal cells |