Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
Mich JK, Sunil S, Johansen N, Martinez RA, Leytze M, Gore BB, Mahoney JT, Ben-Simon Y, Bishaw Y, Brouner K, Campos J, Canfield R, Casper T, Dee N, Egdorf T, Gary A, Gibson S, Goldy J, Groce EL, Hirschstein D, Loftus L, Lusk N, Malone J, Martin NX, Monet D, Omstead V, Opitz-Araya X, Oster A, Pom CA, Potekhina L, Reding M, Rimorin C, Ruiz A, Sedeño-Cortés AE, Shapovalova NV, Taormina M, Taskin N, Tieu M, Valera Cuevas NJ, Weed N, Way S, Yao Z, McMillen DA, Kunst M, McGraw M, Thyagarajan B, Waters J, Bakken TE, Yao S, Smith KA, Svoboda K, Podgorski K, Kojima Y, Horwitz GD, Zeng H, Daigle TL, Lein ES, Tasic B, Ting JT, Levi BP
bioRxiv 2023.09.20.558718
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Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 208120 | AiP12979 - pAAV-AiE0361h-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2979) | AiE0361h is an enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes |
| 208121 | AiP12141 - pAAV-AiE0371h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2141) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208122 | AiP12144 - pAAV-AiE0376h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2144) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208123 | AiP13098 - pAAV-AiE0380h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN3098) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208124 | AiP12146 - pAAV-AiE0381h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2146) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208125 | AiP12495 - pAAV-AiE0385h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2495) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208126 | AiP12153 - pAAV-AiE0390h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2153) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208128 | AiP12084 - pAAV-AiE0373m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2084) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208129 | AiP12098 - pAAV-AiE0374m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2098) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208130 | AiP12085 - pAAV-AiE0375m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2085) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208131 | AiP12122 - pAAV-AiE0385m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2122) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208132 | AiP12088 - pAAV-AiE0386m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2088) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208133 | AiP12102 - pAAV-AiE0387m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2102) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208134 | AiP12089 - pAAV-AiE0390m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2089) | Direct-expressing SYFP2 in astrocytes AAV Virus |
| 208135 | AiP1346 - pAAV-AiE2E117m-minBGpromoter-SYFP2-WPRE3-bGHpA | Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1346 - pAAV-AiE2117m-minBG-SYFP2-WPRE-BGHpA |
| 208136 | AiP1347 - pAAV-AiE2E118m-minBGpromoter-SYFP2-WPRE3-bGHpA | Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1347 - pAAV-AiE2118m-minBG-SYFP2-WPRE-BGHpA |
| 208137 | AiP1349 - pAAV-AiE2E120m-minBGpromoter-SYFP2-WPRE3-bGHpA | Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1349 - pAAV-AiE2120m-minBG-SYFP2-WPRE-BGHpA |
| 208138 | AiP1457 - pAAV-AiE2E121m-minBGpromoter-SYFP2-WPRE3-bGHpA | Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1457 - pAAV-AiE2121m-minBG-SYFP2-WPRE-BGHpA |
| 208140 | AiP1389 - pAAV-AiE2E160m-minBGpromoter-SYFP2-WPRE3-bGHpA | Direct-expressing SYFP2 in astrocytes AAV Virus. Alias: AiP1389 - pAAV-AiE2160m-minBG-SYFP2-WPRE-BGHpA |
| 208141 | AiP12558 - pAAV-AiE0390m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2558) | AiE0390m_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes |
| 208142 | AiP13568 - pAAV-AiE0387m_3xC1-minBG-SYFP2-WPRE3-BGHpA (Alias: CN3568) | AiE0387m_3xC1 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes |
| 208143 | AiP13572 - pAAV-AiE0390h_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN3572) | AiE0390h_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes |
| 208144 | AiP12556 - pAAV-AiE0410m_3xC-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2556) | AiE0410m_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain oligodendrocytes |
| 208145 | AiP12505 - pAAV-AiE0391h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2505) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208146 | AiP12157 - pAAV-AiE0395h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2157) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208147 | AiP12498 - pAAV-AiE0395m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2498) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208148 | AiP12158 - pAAV-AiE0396h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2158) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208149 | AiP12099 - pAAV-AiE0396m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2099) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208150 | AiP12123 - pAAV-AiE0397m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2123) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208151 | AiP12162 - pAAV-AiE0400h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2162) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208152 | AiP12106 - pAAV-AiE0400m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2106) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208153 | AiP12677 - pAAV-AiE0401h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2677) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208154 | AiP12499 - pAAV-AiE0403h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2499) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208155 | AiP12107 - pAAV-AiE0405m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2107) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208156 | AiP13062 - pAAV-AiE0409h-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN3062) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208157 | AiP12109 - pAAV-AiE0410m-minBglobin-SYFP2-WPRE3-BGHpA (Alias: CN2109) | Direct-expressing SYFP2 in oligodendrocytes AAV Virus |
| 208158 | AiP12845 - pAAV-AiE0641m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2845) | AiE0641m is an enhancer sequence designed to drive AAV-mediated transgene expression in brain oligodendrocytes |
| 208165 | AiP14253 - pAAV-AiE0380h_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN4253) | AiE0380h_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes |
| 214492 | AiP1421 - pAAV-AiE2119m-minBG-SYFP2-WPRE-BGHpA | AiE2119m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells |
| 214493 | AiP1422 - pAAV-AiE2123m-minBG-SYFP2-WPRE-BGHpA | AiE2123m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells |