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A Modular Encapsulation System for Precision Delivery of Proteins, Nucleic Acids, and Small Molecules.

Luong TD, Martel N, Rae J, Lo HP, Lim YW, Wu Y, McMahon KA, Sun H, Fletcher NL, Thurecht KJ, Johnston APR, Ariotti N, Hall TE, Parton RG
ACS Nano. 2025 Dec 23;19(50):42079-42096. doi: 10.1021/acsnano.5c11452. Epub 2025 Dec 12. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
223700pNMTMA_MBP-Cav1-His6To produce standard caveospheres (without the Z-domain), Parton Lab clone LDB
223701pNMTMA_MBP-Z-Cav1-His6To produce z-spheres (caveospheres containing the anti-IgG Z-domain of protein A), Parton Lab clone LCU
223703pNMTMA_MBP_Z_Cav1_H6_Periplasmic_mScarletTo produce caveospheres with periplasmically encapsulated mScarlet
223705DTA in pCDEST2Mammalian expression vector encoding diptheria toxin A
223706pOPINE-GFPFor production of EGFP by E.coli

Antibodies from Article