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Private benefit of beta-lactamase dictates selection dynamics of combination antibiotic treatment.

Ma HR, Xu HZ, Kim K, Anderson DJ, You L
Nat Commun. 2024 Sep 27;15(1):8337. doi: 10.1038/s41467-024-52711-w. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
223806pBla_GFPinducible expression of low-copy Bla and and constitutive expression of GFP
223807pBlaM_GFPinducible expression of low-copy BlaM (cytoplasmic variant) and constitutive expression of GFP
223808pHBla_GFPinducible expression of high-copy Bla and and constitutive expression of GFP
223809pHBlaM_GFPinducible expression of high-copy BlaM (cytoplasmic variant) and constitutive expression of GFP

Antibodies from Article