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Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.

Puyalto A, Rodriguez-Remirez M, Lopez I, Macaya I, Guruceaga E, Olmedo M, Vilalta-Lacarra A, Welch C, Sandiego S, Vicent S, Valencia K, Calvo A, Pio R, Raez LE, Rolfo C, Ajona D, Gil-Bazo I
Mol Cancer. 2024 Apr 20;23(1):78. doi: 10.1186/s12943-024-01991-3. (Link opens in a new window) PubMed (Link opens in a new window) Article

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