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DePARylation is critical for S phase progression and cell survival.

Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, Ma L, Gan B, Chen J
Elife. 2024 Apr 5;12:RP89303. doi: 10.7554/eLife.89303. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
240315pDonr201_PARG WTEntry vector for Gateway with PARG
240316pJFT7_nHalo_DC(r4)_PARG_MutationGateway compatible vector expressing PARG (E755/756A)
240317pDonr201_PARP1Entry vector for Gateway with PARP1
240318pDonr201_PARP1_del119/120Entry vector for Gateway with PARP1 (AA119/120 deletion)

Antibodies from Article