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Specific targeting of brain endothelial cells using enhancer AAV vectors.

Velazquez-Rivera E, Dey O, Kim NS, Cao W, Ye Q, Gao P, Thai A, Nguyen JK, Zhang H, Ting JT, Gopi M, Ren B, Holmes TC, Xu X
Neuron. 2025 May 21;113(10):1562-1578.e6. doi: 10.1016/j.neuron.2025.03.031. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
236724pAAV-BEC enhancer-minBG-CreCre Brain Endothelial Cell Enhancer
236727pAAV-BEC enhancer-minBG-iCre(R279T)-4x6TBrain Endothelial Cell Enhancer with 4x6T miRNA targeting cassette For use in combination with Cre-dependent transgenic mouse lines or co-infection with Cre dependent viral vectors.

Antibodies from Article