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Synthetic Serum Markers Enable Noninvasive Monitoring of Gene Expression in Primate Brains

Lee S, Romac M, Watanabe S, Chernov M, Li H, Raisley E, Szablowski HO, Costa VD
bioRxiv 2025.06.01.657212; doi: 10.1101/2025.06.01.657212 (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
227886pAAV-hSyn-Gluc-NHP.RMA-IRES-EGFPExpresses Gluc-NHP.RMA and EGFP under the hSyn promoter. Gluc-NHP.RMA for monitoring neuronal transduction.
227887pAAV-hSyn-DIO-Gluc-NHP.RMA-IRES-EGFPExpresses Gluc-NHP.RMA and EGFP in the presence of Cre recombinase. Double-floxed Gluc-NHP.RMA and EGFP for monitoring Cre-expressing neuronal populations.
227888pAAV-hSyn-Cluc-NHP.RMAExpresses Cluc-NHP.RMA under the hSyn promoter. Cluc-NHP.RMA for monitoring neuronal transduction.

Antibodies from Article