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De novo design of potent CRISPR-Cas13 inhibitors.

Taveneau C, Chai HX, D'Silva J, Bamert RS, Chen H, Hayes BK, Calvert RW, Purcell J, Curwen DJ, Munder F, Martin LL, Barr JJ, Rosenbluh J, Fareh M, Grinter R, Knott GJ
Nat Chem Biol. 2026 Jan 26. doi: 10.1038/s41589-025-02136-3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
234052pBAD_AIcrVIA1Plasmid for AIcrVIA1 expression during phage assay
234053pBAD_AIcrVIA2Plasmid for AIcrVIA2 expression during phage assay
234054pBAD_AIcrVIA3Plasmid for AIcrVIA3 expression during phage assay

Antibodies from Article