Simulating 500 million years of evolution with a language model.
Hayes T, Rao R, Akin H, Sofroniew NJ, Oktay D, Lin Z, Verkuil R, Tran VQ, Deaton J, Wiggert M, Badkundri R, Shafkat I, Gong J, Derry A, Molina RS, Thomas N, Khan YA, Mishra C, Kim C, Bartie LJ, Nemeth M, Hsu PD, Sercu T, Candido S, Rives A
Science. 2025 Feb 21;387(6736):850-858. doi: 10.1126/science.ads0018. Epub 2025 Jan 16.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 231302 | B8-pVTCB052 | Plasmid used for expression of AI-designed GFP protein B8 in E. coli |
| 231303 | esmGFP-C10-pVTCB052 | Plasmid used for expression of AI-designed GFP protein esmGFP-C10 E. coli |