Skip to main content

The TDG protein environment connects active DNA demethylation with chromatin and RNA biology.

Richina F, Noreen F, Bauer C, Weber A, Kunz C, Buczak K, Schwarz SD, Wu F, Schurmann D, Schar P
Cell Mol Life Sci. 2025 Nov 25. doi: 10.1007/s00018-025-05943-y. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
232025pCMV-NLS-BioID2-HAmammalian expression (CMV promoter) of nuclear targeted BioID2-HA
232026pCMV-H4-BioID2-HAmammalian expression (CMV promoter) of histone H4 fused to BioID2-HA
232027pCMV-mTDGa-BioID2-HAmammalian expression (CMV promoter) of murine TDG fused to BioID2-HA
232028pCMV-mTDGa.1-BioID2-HAmammalian expression (CMV promoter) of murine TDGa.1 (catalytic mutant N151A) fused to BioID2-HA
232029pCMV-mTDGa.2-BioID2-HAmammalian expression (CMV promoter) of TDGa.2 (SIM mutant E321Q) fused to BioID2-HA
232030pPgk-mTDGa-BioID2-HAmammalian expression (murine Pgk promoter) of murine TDG fused to BioID2-HA
232031pPgk-NLS-BioID2-HAmammalian expression (murine Pgk promoter) of nuclear targeted BioID2-HA
232032pGEM-7zf(+)_mmSRA1in vitro transcription of murine Sra1
232033pGEM-3zf(+)_hsSRA1in vitro transcription of human Sra1

Antibodies from Article