Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization.
Li J, Liu S, Kim S, Goell J, Drum ZA, Flores JP, Ma AJ, Mahata B, Escobar M, Raterink A, Ahn JH, Teran ER, Guerra-Resendez RS, Zhou Y, Yu B, Diehl MR, Wang GG, Gustavsson AK, Phanstiel DH, Hilton IB
Nucleic Acids Res. 2025 Feb 8;53(4):gkaf056. doi: 10.1093/nar/gkaf056.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 232754 | EGFP | Expresses EGFP |
| 232755 | EWSR1_IDR-EGFP | Expresses EWSR1_IDR-EGFP |
| 232756 | SS18_IDR-EGFP | Expresses SS18_IDR-EGFP |
| 232757 | NONO1_IDR-EGFP | Expresses NONO1_IDR-EGFP |
| 232758 | NONO2_IDR-EGFP | Expresses NONO2_IDR-EGFP |
| 232759 | NUP98a_IDR-EGFP | Expresses NUP98a_IDR-EGFP |
| 232760 | NUP98b_IDR-EGFP | Expresses NUP98b_IDR-EGFP |
| 232761 | dCas9-EGFP | Expresses dCas9-EGFP |
| 232762 | dCas9-EWSR1_IDR-EGFP | Expresses dCas9-EWSR1_IDR-EGFP |
| 232763 | dCas9-SS18_IDR-EGFP | Expresses dCas9-SS18_IDR-EGFP |
| 232764 | dCas9-NONO1_IDR-EGFP | Expresses dCas9-NONO1_IDR-EGFP |
| 232765 | dCas9-NONO2_IDR-EGFP | Expresses dCas9-NONO2_IDR-EGFP |
| 232766 | dCas9-NUP98a_IDR-EGFP | Expresses dCas9-NUP98a_IDR-EGFP |
| 232767 | dCas9-NUP98b_IDR-EGFP | Expresses dCas9-NUP98b_IDR-EGFP |