Proline substitutions in the ASIC1 beta11-12 linker slow desensitization.
Purohit R, Couch T, Rook ML, MacLean DM
Biophys J. 2024 Oct 15;123(20):3507-3518. doi: 10.1016/j.bpj.2024.08.016. Epub 2024 Sep 3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 233129 | cASIC1 concatemer - Subunit A | To create cASIC1 channels of defined stoichiometry in mammalian cells |
| 233130 | cASIC1 concatemer - Subunit B | To create cASIC1 channels of defined stoichiometry in mammalian cells |
| 233131 | cASIC1 concatemer - Subunit C | To create cASIC1 channels of defined stoichiometry in mammalian cells |
| 233132 | cASIC1 concatemer - vector backbone | To create cASIC1 channels of defined stoichiometry in mammalian cells |
| 233133 | cASIC1 concatemer - fully assembled | To create cASIC1 channels of defined stoichiometry in mammalian cells |