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Mechanically knocking out titin reveals protein tension loss as a trigger of muscle disease.

Silva-Rojas R, Vicente N, Gavilan-Herrera M, Labrador-Cantarero V, Sicilia J, Gimenez-Saez O, Dumitru AC, Sanchez MI, Gato-Vilaseca M, Velazquez-Carreras D, Lopez JA, Vazquez J, Herrero-Galan E, Lopez-Unzu MA, Pricolo MR, Alegre-Cebollada J
Nat Biomed Eng. 2025 Jun 5. doi: 10.1038/s41551-025-01403-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
234320pCMV-eGFP-uTEV3Mammalian expression of uTEV3 tagged with an eGFP marker

Antibodies from Article