An in vivo barcoded CRISPR-Cas9 screen identifies Ncoa4-mediated ferritinophagy as a dependence in Tet2-deficient hematopoiesis.
Loke J, Kim PG, Nguyen TTP, Boileau M, McConkey M, Miller AP, Shin W, Hergott CB, Ericsson M, Nordstrom A, Montero-Llopis P, Armstrong SA, Mancias JD, Ebert BL
Blood. 2025 Jun 10:blood.2024028033. doi: 10.1182/blood.2024028033.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
234819 | UMI-sgRNA-TF | Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice. |
234820 | UMI-sgRNA-CH | Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice. |