A toolbox for ablating excitatory and inhibitory synapses.
Bareghamyan A, Deng C, Daoudi S, Yadav SC, Lu X, Zhang W, Campbell RE, Kramer RH, Chenoweth DM, Arnold DB
eLife. 2025 Apr 29;13:RP103757. doi: 10.7554/eLife.103757.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 236113 | eDHFR-E3 | Half of chemically inducible GFE3. When co-expressed with 236112 can degrade inhibitory synapses in presence of TH. (trimethoprim-HaloTag ligand). |
| 236178 | AAV-CAG-PFE3-P2A-GFP | AAV version of constitutive PFE3 for ablating excitatory synapses. |
| 236180 | AAV-TRE-PFE3-P2A-GFP | AAV version of Tet inducible PFE3 for ablating excitatory synapses. |
| 236181 | AAV-CAG-RandE3-P2A-GFP | AAV version of constitutive control plasmid |