Fbxw7alpha- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma.
Busino L, Millman SE, Scotto L, Kyratsous CA, Basrur V, O'Connor O, Hoffmann A, Elenitoba-Johnson KS, Pagano M
Nat Cell Biol. 2012 Mar 4;14(4):375-85. doi: 10.1038/ncb2463.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 236468 | pBABE FLAG HA p100 | stable expression of p100 using virus infection |
| 236469 | pBABE FLAG HA p100 (Ser707/711Ala) | stable expression of p100 using virus infection |
| 236470 | pcDNA3 FLAG FBXW7alpha | transient overexpression of FBXW7alpha in mammalian cells |
| 236471 | pcDNA3 FLAG Fbxw7gamma | transient overexpression of FBXW7gamma in mammalian cells |