KBG syndrome-associated protein ANKRD11 regulates SETD5 expression to modulate rRNA levels and translation.
Sashiyama S, Nakagawa T, Nakagawa M, Hosogane M, Watanabe Y, Ashitomi H, Yamane K, Shibuya N, Moroishi T, Nakayama K, Hosoi T
iScience. 2025 May 19;28(6):112699. doi: 10.1016/j.isci.2025.112699. eCollection 2025 Jun 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 236608 | pSpCas9(BB)-2A-puro-mAnkrd11 (intron 3) | Knockouts Ankrd11 in mouse cells |
| 236612 | pSpCas9(BB)-2A-puro-hANKRD11 (exon 5-1) | Knockouts ANKRD11 in human cells |
| 236613 | pSpCas9(BB)-2A-puro-hANKRD11 (exon 5-2) | Knockouts ANKRD11 in human cells |
| 236614 | pCAG-puro-9xmyc-WDR5 | Expresses human WDR5 in mammalian cells |
| 236616 | PB-TA-ERN-SETD5 | Expresses human SETD5 in mammalian cells |
| 236618 | pCAG-puro-3xFLAG-ANKRD11-3xHA fragment 1 | Expresses human ANKRD11 fragment in mammalian cells |
| 236619 | pCAG-puro-3xFLAG-ANKRD11-3xHA fragment 2 | Expresses human ANKRD11 fragment in mammalian cells |
| 236623 | pCAG-puro-3xFLAG-ANKRD11-3xHA fragment 6 | Expresses human ANKRD11 fragment in mammalian cells |
| 236721 | PB-TA-ERN-WDR5-FLAG | Expresses human WDR5 in mammalian cells |