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Allosteric activation mechanism of DriD, a WYL-domain containing transcription regulator.

Cannistraci E, Srinivasu BY, Chavez Orozco J Jr, Gozzi K, Wales TE, Schumacher MA
Commun Biol. 2025 Apr 29;8(1):679. doi: 10.1038/s42003-025-08111-x. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
237851DriD-wHTH-DNABDThe wHTH DNA binding domain used to understand the allosteric mechanism
237852DriD-3HB-mutantDriD 3HB surface mutant used to interrogate the allosteric mechanism
237853DriD_78-327DriD missing the wHTH DNABD used to crystallize the apo protein

Antibodies from Article