Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Sun X, Ferguson JA, Yang K, Stanfield RL, Dyson HJ, Wright PE
Protein Sci. 2024 Sep;33(9):e5101. doi: 10.1002/pro.5101.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 238110 | TTR A120L | bacterial expression of human TTR mutant |
| 238112 | TTR C10S/S85C/A120L | bacterial expression of human TTR mutant |
| 238113 | TTR C10S/S85C/A120S | bacterial expression of human TTR mutant |