A split luciferase biosensing platform for detection and imaging of chromatin loops in individual live cells.

Heath NG, Gomez JA, McGinty SP, O'Geen H, Segal DJ
Nucleic Acids Res. 2025 Nov 26;53(22):gkaf1324. doi: 10.1093/nar/gkaf1324. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
236758	LgBiT-dSaCas9	Split NanoLuc luciferase biosensor fused to dSaCas9
236759	dSpCas9-SmBiT	Split NanoLuc luciferase biosensor fused to dSpCas9
238946	HaloTag-dSpCas9	N-terminal fusion of HaloTag to dSpCas9, mammalian expression
238947	dSaCas9-NLuc	C-terminal fusion of NanoLuc luciferase to dSaCas9, mammalian expression