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Free introns of tRNAs as complementarity-dependent regulators of gene expression.

Nostramo RT, Sinopoli PL, Bao A, Metcalf S, Peltier LM, Hopper AK
Mol Cell. 2025 Feb 20;85(4):726-741.e6. doi: 10.1016/j.molcel.2025.01.019. Epub 2025 Feb 11. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
239294T7pro-tRNA-ITSIle intron-T7tVar1-pRS426Expresses the tRNAIle intron bearing the 5' GGGAGA initially transcribed sequence (ITS); Plasmid #2 of the tet-on overexpression system

Antibodies from Article